Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PGK1 | P00558 | 1/20 | 0.31 |
| ▸ | PGK2 | P07205 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097993 | 0.88 | ALDH1A1 (0.46) | ALDH1A1TSHRNPSR1PPARDMAPT | |
| SCHEMBL3098905 | 0.87 | FPR2 (0.45) | ALDH1A1TSHRNPSR1PPARDFPR2 | |
| SCHEMBL3100652 | 0.85 | TSHR (0.35) | TSHRPPARDMAPTMAPK1FPR2 | |
| SCHEMBL3094628 | 0.81 | TSHR (0.42) | ALDH1A1TSHRPPARDMAPTMAPK1 | |
| SCHEMBL3091512 | 0.78 | MAPT (0.56) | ALDH1A1TSHRNPSR1MAPTMAPK1 | |
| SCHEMBL29941107 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRNPSR1MAPTMAPK1 | |
| SCHEMBL2985648 | 0.77 | PGK1 (0.35) | ALDH1A1CA1CA2PGK1PGK2 | |
| SCHEMBL2817679 | 0.77 | PGK1 (0.35) | ALDH1A1CA1CA2PGK1PGK2 | |
| SCHEMBL2817677 | 0.77 | PGK1 (0.35) | ALDH1A1CA1CA2PGK1PGK2 | |
| SCHEMBL3097313 | 0.77 | TSHR (0.36) | ALDH1A1TSHRNPSR1PPARDFPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |