Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | CPA1 | P15085 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097993 | 0.88 | ALDH1A1 (0.46) | FPR2ALDH1A1CA2CA1TSHR | |
| SCHEMBL3102486 | 0.87 | FPR2 (0.44) | FPR2ALDH1A1L3MBTL1CA2CA1 | |
| SCHEMBL3095559 | 0.87 | ALDH1A1 (0.38) | FPR2ALDH1A1CA2CA1TSHR | |
| SCHEMBL3094628 | 0.81 | TSHR (0.42) | FPR2ALDH1A1CA2CA1TSHR | |
| SCHEMBL2991878 | 0.79 | ALDH1A1 (0.50) | FPR2ALDH1A1L3MBTL1CA2CA1 | |
| SCHEMBL2991880 | 0.79 | ALDH1A1 (0.50) | FPR2ALDH1A1L3MBTL1CA2CA1 | |
| SCHEMBL3097313 | 0.77 | TSHR (0.36) | FPR2ALDH1A1CA2CA1TSHR | |
| SCHEMBL9505346 | 0.75 | FPR2 (0.46) | FPR2ALDH1A1MEN1KMT2A | |
| SCHEMBL3100652 | 0.75 | TSHR (0.35) | FPR2CA2CA1TSHRPPARD | |
| SCHEMBL3090822 | 0.75 | FPR2 (0.46) | FPR2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |