Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098905 | 0.88 | FPR2 (0.45) | ALDH1A1NPSR1TSHRPPARDFPR2 | |
| SCHEMBL3095559 | 0.88 | ALDH1A1 (0.38) | ALDH1A1NPSR1TSHRPPARDFPR2 | |
| SCHEMBL3097313 | 0.85 | TSHR (0.36) | ALDH1A1NPSR1TSHRPPARDFPR2 | |
| SCHEMBL14502980 | 0.82 | CA12 (0.36) | ALDH1A1NPSR1SMN1; SMN2PLA2G2APLA2G5 | |
| SCHEMBL3094628 | 0.82 | TSHR (0.42) | ALDH1A1TSHRPPARDFPR2KDM4E | |
| SCHEMBL9505346 | 0.77 | FPR2 (0.46) | ALDH1A1FPR2PLA2G2APLA2G5MAPT | |
| SCHEMBL3090822 | 0.77 | FPR2 (0.46) | ALDH1A1FPR2PLA2G2APLA2G5MAPT | |
| SCHEMBL3100652 | 0.77 | TSHR (0.35) | TSHRPPARDFPR2MAPTMAPK1 | |
| SCHEMBL3091512 | 0.76 | MAPT (0.56) | ALDH1A1NPSR1TSHRFPR2SMN1; SMN2 | |
| SCHEMBL3094248 | 0.76 | PPARD (0.41) | TSHRPPARDFPR2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |