Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 6/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109175 | 0.84 | TSHR (0.39) | TSHRALDH1A1KDM4EPPARDMAPT | |
| SCHEMBL3097993 | 0.82 | ALDH1A1 (0.46) | TSHRALDH1A1KDM4EPPARDMAPT | |
| SCHEMBL3095559 | 0.81 | ALDH1A1 (0.38) | TSHRALDH1A1KDM4EPPARDMAPT | |
| SCHEMBL3098905 | 0.81 | FPR2 (0.45) | TSHRALDH1A1KDM4EPPARDFPR2 | |
| SCHEMBL3090822 | 0.80 | FPR2 (0.46) | ALDH1A1MAPTFPR2 | |
| SCHEMBL9505346 | 0.80 | FPR2 (0.46) | ALDH1A1MAPTFPR2 | |
| SCHEMBL3094248 | 0.79 | PPARD (0.41) | TSHRPPARDMAPTMAPK1FPR2 | |
| SCHEMBL3101417 | 0.77 | CA2 (0.40) | TSHRPPARDMAPTMAPK1FPR2 | |
| SCHEMBL3108084 | 0.77 | MAPT (0.42) | TSHRKDM4EPPARDMAPTMAPK1 | |
| SCHEMBL3098722 | 0.77 | FPR2 (0.43) | TSHRPPARDMAPTMAPK1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100247463-A1 | N-(PHOSPHONOALKYL)-AMINO ACIDS, DERIVATIVES THEREOF AND COMPOSITIONS AND METHODS OF USE | YU RUEY J | 2010-09-30 | — | — | US | claimed |