SCHEMBL30980667

SCHEMBL30980667

CS(=O)(=O)OCC1CCN(c2ccccc2)CC1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RORC P51449 3/20 0.47
ACHE P22303 4/20 0.43
CYP2C9 P11712 1/20 0.43
ALDH1A1 P00352 1/20 0.43
PKM P14618 1/20 0.43
GAA P10253 1/20 0.43
KMT2A Q03164 1/20 0.42
HRH3 Q9Y5N1 1/20 0.42
HCRTR2 O43614 1/20 0.42
MBTD1 Q05BQ5 1/20 0.41
L3MBTL3 Q96JM7 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
GPR119 Q8TDV5 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6895764 0.85 CYP2C19 (0.46) CYP2C9HRH3GPR119
SCHEMBL9174457 0.83 GPR119 (0.47) RORCHRH3GPR119
SCHEMBL1660780 0.79 CTSG (0.42) ALDH1A1KMT2A
SCHEMBL8508214 0.79 GPR119 (0.54) ALDH1A1KMT2AHRH3L3MBTL1GPR119
SCHEMBL27827078 0.79 RORC (0.52) RORCACHEHRH3MBTD1L3MBTL3
SCHEMBL6926829 0.78 CHRM3 (0.38) RORCALDH1A1
SCHEMBL21770159 0.78 LMNA (0.50) ALDH1A1GAAKMT2AHCRTR2L3MBTL1
SCHEMBL8549864 0.77 ACHE (0.56) ACHEGAAKMT2AL3MBTL3L3MBTL1
SCHEMBL15261159 0.77 MAPT (0.51) CYP2C9ALDH1A1GAAKMT2AHRH3
SCHEMBL31330847 0.77 GPR119 (0.47) KMT2AGPR119

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676926-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS ThirtyFiveBio Limited (GB) 2026-01-14 EP disclosed
EP-4651902-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES Lycia Therapeutics, Inc. (US) 2025-11-26 EP disclosed
WO-2024184650-A1 BICYCLIC HETEROARYL COMPOUNDS FOR USE AS GPR35 MODULATORS. ThirtyFiveBio Limited (GB) 2024-09-12 WO disclosed
WO-2024155747-A2 ASGPR BINDING COMPOUNDS AND CONJUGATES LYCIA THERAPEUTICS, INC. (US) 2024-07-25 WO disclosed