SCHEMBL30985

SCHEMBL30985

Cc1ccc(C#N)c(F)c1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 2/20 0.57
CYP11B1 P15538 13/20 0.54
CYP11B2 P19099 13/20 0.54
AR P10275 3/20 0.46
EGLN2 Q96KS0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12326411 0.86 CYP11B1 (0.55) TRPV4CYP11B1CYP11B2
SCHEMBL16604315 0.86 CYP11B1 (0.55) TRPV4CYP11B1CYP11B2
Formic Acid Methyl Ester SCHEMBL28324376 0.86 CYP11B1 (0.44) TRPV4CYP11B1CYP11B2AR
SCHEMBL12012339 0.84 CYP11B1 (0.66) TRPV4CYP11B1CYP11B2AR
SCHEMBL253758 0.82 TRPV4 (0.43) TRPV4CYP11B1CYP11B2AR
SCHEMBL14228701 0.82 CYP11B1 (0.59) CYP11B1CYP11B2AR
SCHEMBL22563167 0.82 PGR (0.42) TRPV4CYP11B1CYP11B2EGLN2
SCHEMBL9293782 0.81 CYP11B1 (0.50) TRPV4CYP11B1CYP11B2AR
SCHEMBL16604328 0.80 CYP11B1 (0.50) CYP11B1CYP11B2
SCHEMBL8265080 0.79 CYP11B1 (0.65) CYP11B1CYP11B2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 858 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023099777-A1 METHOD OF UNDERWATER BONDING Henkel IP & Holding GmbH (DE) 2023-06-08 WO claimed
EP-3692101-B1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTR S R L (IT) 2022-01-12 EP claimed
EP-3692101-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES Alfa Instruments S.r.l. (IT) 2020-08-12 EP claimed
WO-2019068935-A1 BRILLIANT BLUE (BBG) DYE DERIVATIVES AND STAINING COMPOSITIONS COMPRISING THE SAME FOR SELECTIVELY STAINING BIOLOGICAL SUBSTRATES ALFA INSTRUMENTS S.R.L. (IT) 2019-04-11 WO claimed
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
US-20250338848-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-11-06 US disclosed
US-12435061-B2 Compounds and compositions for use in treating skin disorders KAMARI PHARMA LTD. (IL) 2025-10-07 US disclosed
EP-4574822-A2 COMPOUNDS AND COMPOSITIONS FOR USE IN TREATING SKIN DISORDERS Kamari Pharma Ltd. (IL) 2025-06-25 EP disclosed
US-20250122226-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES NOVO NORDISK AS (DK) 2025-04-17 US disclosed
CN-119768407-A Protein phosphatase agonist and application thereof 南京中瑞药业有限公司 2025-04-04 CN disclosed
US-20250100981-A1 Cis-substituted 5-(hydroxymethyl)morpholine-2-carboxamides as agonists of SSTR4 BOEHRINGER INGELHEIM INT (DE) 2025-03-27 US disclosed
CN-119661371-A Preparation method of 2-fluoro-4-methylaniline 帕潘纳(北京)科技有限公司 2025-03-21 CN disclosed
CN-1030682-C Method for preparating N-aryl-3-aryl-4.5-dihydro-IH-pyrazole-l-carboxamides ROHM AND HASS CORP (US) 1996-01-17 CN disclosed
US-5340497-A Ferroelectric liquid crystal MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1994-08-23 US disclosed
US-4784471-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1988-11-15 US disclosed
EP-0211876-A1 FLUOROBENZENE DERIVATIVES MERCK PATENT GmbH (DE) 1987-03-04 EP disclosed
WO-1986004895-A1 FLUOROBENZENE DERIVATIVES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1986-08-28 WO disclosed
CN-85101497-A Process for the preparation of N-aryl-3-aryl-4, 5-dihydro-1H-pyrazole-1-carboxamides 1986-07-16 CN disclosed
EP-0061907-B1 SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE BEECHAM GROUP PLC (GB) 1984-08-01 EP disclosed
EP-0061907-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1982-10-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12435061-B2 Compounds and compositions for use in treating skin disorders RDX, HAX1, F12 TRPV4 1346/4885CYP11B1 796/4885CYP11B2 786/4885
US-20250338848-A1 FUNGICIDAL COMPOSITIONS CYP3A7, DHCR7, CASP7 TRPV4 2822/4885CYP11B1 251/4885CYP11B2 328/4885
US-20250122226-A1 GLUCOSE-SENSITIVE ALBUMIN-BINDING DERIVATIVES ALB, DBI, FABP4 TRPV4 4000/4885CYP11B1 4034/4885CYP11B2 4172/4885
US-20250100981-A1 Cis-substituted 5-(hydroxymethyl)morpholine-2-carboxamides as agonists of SSTR4 SSTR4, SSTR5, SSTR2 TRPV4 250/4885CYP11B1 816/4885CYP11B2 499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.