Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989806 | 0.92 | GRM5 (0.45) | ALDH1A1HPGDMEN1KMT2ARIPK1 | |
| SCHEMBL30989812 | 0.91 | MEP1B (0.44) | ALDH1A1HPGDMEN1KMT2ARIPK1 | |
| SCHEMBL30989972 | 0.91 | ALDH1A1 (0.49) | ALDH1A1HPGDMEN1KMT2ASCD5 | |
| SCHEMBL30989857 | 0.90 | HSP90AA1 (0.52) | KMT2AHSP90AA1HSD17B1HSD17B2HTT | |
| SCHEMBL30989808 | 0.89 | HTT (0.39) | ALDH1A1HPGDCLK1CLK2DYRK1A | |
| SCHEMBL30989909 | 0.89 | CLK1 (0.48) | ALDH1A1HPGDMEN1KMT2ASCD5 | |
| SCHEMBL30989922 | 0.88 | POLB (0.49) | ALDH1A1HPGDMEN1KMT2ARIPK1 | |
| SCHEMBL30989793 | 0.88 | HTT (0.38) | ALDH1A1HPGDMEN1KMT2ACLK1 | |
| SCHEMBL30989807 | 0.87 | TACR1 (0.47) | HPGDPTGER4 | |
| SCHEMBL30989861 | 0.86 | RIPK1 (0.49) | HPGDRIPK1PTGER4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |