Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GPR6 | P46095 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30989901 | 0.81 | RIPK1 (0.46) | RIPK1NPC1GPR6KDM4EALDH1A1 | |
| SCHEMBL30989936 | 0.81 | RIPK1 (0.47) | RIPK1NPC1GPR6KDM4EALDH1A1 | |
| SCHEMBL30989921 | 0.78 | RIPK1 (0.45) | RIPK1GPR6KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL30989804 | 0.76 | RIPK1 (0.45) | RIPK1GPR6KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL5643407 | 0.71 | RIPK1 (0.56) | RIPK1ALDH1A1MEN1KMT2ATAS2R14 | |
| SCHEMBL30989942 | 0.71 | RIPK1 (0.45) | RIPK1GPR6MEN1KMT2AL3MBTL1 | |
| SCHEMBL5647030 | 0.70 | KMT2A (0.58) | RIPK1MEN1KMT2A | |
| SCHEMBL30989827 | 0.70 | PIK3C3 (0.41) | RIPK1NPC1GPR6MEN1KMT2A | |
| SCHEMBL30989882 | 0.69 | MEN1 (0.48) | RIPK1NPC1KDM4EALDH1A1MEN1 | |
| SCHEMBL30989925 | 0.69 | RIPK1 (0.42) | RIPK1GPR6L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4612131-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2025-09-10 | — | — | EP | disclosed |
| WO-2024095003-A1 | NICOTINAMIDE DERIVATIVES FOR USE IN TREATING DISORDERS ASSOCIATED WITH KCNK13 ACTIVITY | Cerevance, Inc. (US) | 2024-05-10 | — | — | WO | disclosed |