Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30995119 | 0.94 | PIK3CA (0.38) | ABL1PLA2G10PLA2G2APIK3CAPRKDC | |
| SCHEMBL30995252 | 0.80 | PLA2G10 (0.42) | ABL1PLA2G10PLA2G2APIK3CAPRKDC | |
| SCHEMBL30995156 | 0.75 | PLA2G10 (0.43) | ABL1PLA2G10PLA2G2APIK3CAPRKDC | |
| SCHEMBL30995228 | 0.74 | NOD2 (0.41) | PLA2G10PLA2G2APIK3CAPRKDCOPRM1 | |
| SCHEMBL30995162 | 0.70 | CYP11B2 (0.44) | CYP11B1CYP11B2OPRM1 | |
| SCHEMBL30995117 | 0.69 | CYP11B2 (0.44) | CYP11B1CYP11B2 | |
| SCHEMBL30995223 | 0.67 | ROCK1 (0.46) | OPRM1NPC1RAB9AKMT2A | |
| SCHEMBL30995183 | 0.67 | PRKACA (0.37) | KMT2A | |
| SCHEMBL30995124 | 0.67 | ALDH1A1 (0.42) | CYP11B1CYP11B2BACE1KMT2A | |
| SCHEMBL13152302 | 0.66 | PIK3CA (0.36) | PIK3CAPRKDCPDE7ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118530160-A | Aromatic heterocyclic compound, preparation method and application thereof | 上海翊石医药科技有限公司 | 2024-08-23 | — | — | CN | disclosed |