Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27776366 | 0.88 | HTT (0.40) | HTTCYP2C9CYP2C19 | |
| SCHEMBL30998997 | 0.81 | LMNA (0.34) | — | |
| SCHEMBL27796919 | 0.75 | APLNR (0.37) | CYP2C19 | |
| SCHEMBL27498670 | 0.75 | ALDH1A1 (0.37) | — | |
| SCHEMBL29348329 | 0.74 | HTT (0.35) | HTTCYP2C9CYP2C19 | |
| SCHEMBL25222546 | 0.73 | ALOX5 (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL27828808 | 0.73 | ALOX5 (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL25222547 | 0.73 | ALOX5 (0.43) | CYP2C9CYP2C19 | |
| SCHEMBL28880383 | 0.73 | HTT (0.35) | HTTCYP2C9CYP2C19 | |
| SCHEMBL28880382 | 0.73 | HTT (0.35) | HTTCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250042857-A1 | SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure | HAIHE BIOPHARMA CO., LTD. (CN) | 2025-02-06 | — | — | US | disclosed |
| EP-4410790-A1 | SOS1 INHIBITORS HAVING PYRIDO SIX-MEMBERED RING STRUCTURE | Haihe Biopharma Co., Ltd. (CN) | 2024-08-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250042857-A1 | SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure | SOS1, MEN1, BRCA1 | HTT 4771/4885CYP2C9 2374/4885CYP2C19 2515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.