Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 6/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9872117 | 0.84 | FABP4 (0.77) | FBP1ALDH1A1KDM4EPKMLMNA | |
| SCHEMBL9871347 | 0.84 | FABP4 (0.77) | FBP1ALDH1A1KDM4EPKMLMNA | |
| SCHEMBL9870700 | 0.84 | FABP4 (0.77) | FBP1ALDH1A1KDM4EPKMLMNA | |
| SCHEMBL2006185 | 0.84 | L3MBTL1 (0.64) | ALDH1A1KDM4EPKMLMNASMN1; SMN2 | |
| SCHEMBL17843468 | 0.84 | L3MBTL1 (0.64) | ALDH1A1KDM4EPKMLMNASMN1; SMN2 | |
| SCHEMBL31014170 | 0.83 | LMNA (0.56) | FBP1ALDH1A1KDM4EPKMLMNA | |
| SCHEMBL7613900 | 0.83 | TBXA2R (0.62) | ALDH1A1KDM4EPKMLMNASMN1; SMN2 | |
| SCHEMBL8595157 | 0.82 | ALDH1A1 (0.82) | ALDH1A1KDM4EPKMLMNASMN1; SMN2 | |
| SCHEMBL6675598 | 0.82 | ALDH1A1 (0.82) | ALDH1A1KDM4EPKMLMNASMN1; SMN2 | |
| SCHEMBL12570968 | 0.82 | ATM (0.65) | ALDH1A1KDM4EPKMLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549306-A4 | SUBSTITUTED PHENYLSULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH CORP (US) | 2007-06-06 | — | — | EP | disclosed |
| EP-1549306-A1 | SUBSTITUTED PHENYLSULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | Wyeth (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003103660-A1 | SUBSTITUTED PHENYLSULFONAMIDE INHIBITORS OF BETA AMYLOID PRODUCTION | WYETH (US) | 2003-12-18 | — | — | WO | disclosed |