Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028235 | 0.86 | TSHR (0.44) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E | |
| SCHEMBL31028268 | 0.85 | PKLR (0.45) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E | |
| SCHEMBL31028281 | 0.85 | PKLR (0.45) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E | |
| SCHEMBL31028249 | 0.85 | L3MBTL1 (0.52) | ALDH1A1HPGDKDM4ERAB9AGAA | |
| SCHEMBL31028237 | 0.84 | MAPT (0.37) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E | |
| SCHEMBL31028223 | 0.83 | MAPT (0.41) | ALDH1A1SMN1; SMN2HPGDKDM4ERAB9A | |
| SCHEMBL31028242 | 0.83 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E | |
| SCHEMBL9460076 | 0.82 | PKM (0.55) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E | |
| SCHEMBL31028244 | 0.81 | MAPT (0.43) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E | |
| SCHEMBL31028226 | 0.69 | CYP1A2 (0.42) | ALDH1A1SMN1; SMN2HPGDNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |