Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028223 | 0.89 | MAPT (0.41) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL31028233 | 0.84 | ALDH1A1 (0.43) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31028235 | 0.82 | TSHR (0.44) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31028249 | 0.81 | L3MBTL1 (0.52) | MAPTLMNANPC1RAB9AGAA | |
| SCHEMBL31028242 | 0.79 | ALDH1A1 (0.44) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9460076 | 0.78 | PKM (0.55) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31028244 | 0.76 | MAPT (0.43) | MAPTLMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL31028281 | 0.70 | PKLR (0.45) | MAPTLMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL31028268 | 0.70 | PKLR (0.45) | MAPTLMNASMN1; SMN2RAB9AMEN1 | |
| SCHEMBL164673 | 0.68 | TSHR (0.52) | MAPTLMNASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |