Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9460076 | 0.83 | PKM (0.55) | MAPTSMN1; SMN2LMNAHTTHSP90AA1 | |
| SCHEMBL31028233 | 0.81 | ALDH1A1 (0.43) | MAPTSMN1; SMN2LMNAHTTHSP90AA1 | |
| SCHEMBL31028242 | 0.81 | ALDH1A1 (0.44) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL31028249 | 0.80 | L3MBTL1 (0.52) | MAPTLMNAHTTKDM4EALDH1A1 | |
| SCHEMBL31028235 | 0.78 | TSHR (0.44) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL31028234 | 0.76 | KDM4E (0.47) | MAPTSMN1; SMN2LMNAKDM4EALDH1A1 | |
| SCHEMBL31028237 | 0.76 | MAPT (0.37) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL31028223 | 0.75 | MAPT (0.41) | MAPTSMN1; SMN2HSP90AA1KDM4EALDH1A1 | |
| SCHEMBL31028226 | 0.70 | CYP1A2 (0.42) | MAPTSMN1; SMN2LMNAHTTHSP90AA1 | |
| SCHEMBL31028264 | 0.70 | CYP1A2 (0.42) | MAPTSMN1; SMN2LMNAHTTHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |