Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | FGB | P02675 | 1/20 | 0.41 |
| ▸ | GRM6 | O15303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | DBF4 | Q9UBU7 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31028226 | 0.84 | CYP1A2 (0.42) | CYP1A2FGBMAPTLMNAHSP90AA1 | |
| SCHEMBL31028257 | 0.81 | KDM4E (0.42) | CYP1A2FGBMAPTLMNAHSP90AA1 | |
| SCHEMBL9460076 | 0.77 | PKM (0.55) | MAPTLMNAHSP90AA1HTTSMN1; SMN2 | |
| SCHEMBL31028234 | 0.76 | KDM4E (0.47) | CYP1A2FGBMAPTLMNASMN1; SMN2 | |
| SCHEMBL8285727 | 0.74 | LMNA (0.36) | LMNAHTTSMN1; SMN2ALDH1A1PKM | |
| SCHEMBL31028244 | 0.70 | MAPT (0.43) | CYP1A2MAPTLMNAHSP90AA1HTT | |
| SCHEMBL31028233 | 0.69 | ALDH1A1 (0.43) | CYP1A2MAPTLMNAHSP90AA1HTT | |
| SCHEMBL13440446 | 0.69 | NOTUM (0.33) | CYP1A2LMNASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL8493097 | 0.69 | CA12 (0.66) | CYP1A2GRM6MAPTLMNAALDH1A1 | |
| SCHEMBL3330772 | 0.68 | TSHR (0.58) | CYP1A2HTTALDH1A1KDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118459481-A | Sulfonyl lactam tetrahydropyridine compound containing exocyclic methylene and preparation method thereof | 安徽久易农业股份有限公司 | 2024-08-09 | — | — | CN | disclosed |