Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049367 | 0.70 | GRIN2B (0.36) | KDM4EL3MBTL1ALDH1A1NPSR1MAPT | |
| SCHEMBL31049343 | 0.70 | GRIN2B (0.32) | KDM4EL3MBTL1ALDH1A1NPSR1ICMT | |
| SCHEMBL31049266 | 0.68 | L3MBTL1 (0.33) | KDM4EL3MBTL1ALDH1A1MAPTGSK3B | |
| SCHEMBL31049264 | 0.67 | SMN1; SMN2 (0.45) | L3MBTL1NPSR1MAPTGSK3BHTT | |
| SCHEMBL31049393 | 0.64 | ICMT (0.41) | L3MBTL1ALDH1A1MAPTKMT2AHTT | |
| SCHEMBL5539875 | 0.63 | GRM5 (0.40) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL31371751 | 0.62 | SCN9A (0.51) | MAPTMEN1KMT2AHTTTSHR | |
| SCHEMBL30047373 | 0.61 | CYP19A1 (0.58) | ALDH1A1MAPTTSHRGAASMN1; SMN2 | |
| SCHEMBL31049571 | 0.61 | ALDH1A1 (0.36) | KDM4EALDH1A1KMT2AHTTICMT | |
| SCHEMBL7100687 | 0.61 | DAO (0.43) | L3MBTL1ALDH1A1MAPTHTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |