Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31049365 | 0.74 | HTT (0.36) | L3MBTL1TDP1MAPT | |
| SCHEMBL27835978 | 0.62 | OXER1 (0.48) | KDM4EALDH1A1NR3C1MEN1KMT2A | |
| SCHEMBL28740845 | 0.61 | KDM4E (0.44) | KDM4EALDH1A1NR3C1MEN1KMT2A | |
| SCHEMBL7100687 | 0.58 | DAO (0.43) | ALDH1A1L3MBTL1MAPT | |
| SCHEMBL31049353 | 0.58 | KDM4E (0.33) | KDM4EALDH1A1L3MBTL1NPSR1MAPT | |
| SCHEMBL26316767 | 0.57 | HRH1 (0.47) | ALDH1A1L3MBTL1MAPTKMT2A | |
| SCHEMBL25784580 | 0.57 | KDM4E (0.41) | KDM4EALDH1A1L3MBTL1NPSR1TDP1 | |
| SCHEMBL45207 | 0.56 | TLR8 (0.44) | ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL10776402 | 0.55 | DAO (0.35) | KDM4EKMT2A | |
| SCHEMBL17672585 | 0.55 | USP14 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118359627-A | MTA synergistic PRMT5 inhibitor compounds having a tetracyclic fused ring structure | 烨辉医药科技(上海)有限公司 | 2024-07-19 | — | — | CN | disclosed |