Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.42 |
| ▸ | TRPC4 | Q9UBN4 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834083 | 0.93 | TRPC5 (0.49) | TRPC5TRPC4KCNH2TRPC1SMN1; SMN2 | |
| SCHEMBL16076186 | 0.90 | MAPT (0.43) | TRPC5TRPC4KCNH2SMN1; SMN2CYP1A2 | |
| SCHEMBL19374965 | 0.85 | ADORA3 (0.51) | TRPC5TRPC4KCNH2TRPC1HTT | |
| SCHEMBL19505597 | 0.85 | SMN1; SMN2 (0.38) | TRPC5TRPC4KCNH2TRPC1SMN1; SMN2 | |
| SCHEMBL31052954 | 0.85 | P2RX3 (0.42) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16076175 | 0.83 | ADORA3 (0.50) | CYP1A2CYP2C19ADORA3TSHRMAPK1 | |
| SCHEMBL31052936 | 0.80 | TRPC4 (0.53) | TRPC5TRPC4KCNH2TRPC1SMN1; SMN2 | |
| SCHEMBL16028981 | 0.78 | ADORA3 (0.40) | HTTADORA3 | |
| SCHEMBL31052942 | 0.78 | LMNA (0.49) | TRPC5TRPC4KCNH2TRPC1SMN1; SMN2 | |
| SCHEMBL555591 | 0.77 | HTT (0.52) | SMN1; SMN2CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373832-B | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳晶蛋生物医药科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-118373832-A | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳晶蛋生物医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |