Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 14/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18834083 | 0.86 | TRPC5 (0.49) | P2RX3CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL16076186 | 0.85 | MAPT (0.43) | POLBTSHRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL31052938 | 0.85 | TRPC5 (0.42) | P2RX3POLBTSHRALDH1A1CYP1A2 | |
| SCHEMBL19505597 | 0.81 | SMN1; SMN2 (0.38) | POLBTSHRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL19374965 | 0.79 | ADORA3 (0.51) | TSHR | |
| SCHEMBL16076175 | 0.78 | ADORA3 (0.50) | TSHRCYP1A2CYP2C19 | |
| SCHEMBL555591 | 0.77 | HTT (0.52) | POLBTSHRALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL16027860 | 0.75 | ALDH1A1 (0.48) | POLBTSHRKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16028981 | 0.74 | ADORA3 (0.40) | — | |
| SCHEMBL31052942 | 0.71 | LMNA (0.49) | P2RX3POLBKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118373832-B | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳晶蛋生物医药科技有限公司 | 2025-01-28 | — | — | CN | disclosed |
| CN-118373832-A | Macrocyclic compound, pharmaceutical composition and application thereof | 深圳晶蛋生物医药科技有限公司 | 2024-07-23 | — | — | CN | disclosed |