Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CTSV | O60911 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056045 | 0.89 | PTGER1 (0.50) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL31056326 | 0.88 | RAB9A (0.44) | ALDH1A1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31056402 | 0.87 | LMNA (0.43) | ALDH1A1HPGDNPC1RAB9ANOTUM | |
| SCHEMBL31056108 | 0.82 | HPGD (0.50) | HPGDNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL31056125 | 0.80 | CYP2C9 (0.40) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL31056825 | 0.79 | MCL1 (0.47) | ALDH1A1KDM4ESMN1; SMN2MAPTCTSV | |
| SCHEMBL7942139 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| SCHEMBL3599086 | 0.77 | NPC1 (0.40) | ALDH1A1HPGDNPC1RAB9AKDM4E | |
| Lithium Ion SCHEMBL31056412 | 0.77 | RXRA (0.42) | ALDH1A1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL31056459 | 0.77 | FOLH1 (0.45) | ALDH1A1NPC1KDM4ECTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024178390-A1 | COVALENT MODIFIERS OF AKT1 AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2024-08-29 | — | — | WO | disclosed |