SCHEMBL31063293

SCHEMBL31063293

CCC(C)(C)c1cc(F)c(OC)c(B(O)OC)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.33
RXRA P19793 1/20 0.33
PPARG P37231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31063410 0.92 RARG (0.34) RARGRXRAPPARG
SCHEMBL21849062 0.82 RARG (0.36) RARGRXRAPPARG
SCHEMBL31063374 0.76 GABRA1 (0.34)
SCHEMBL31063095 0.75 CA2 (0.40) RARGRXRAPPARG
SCHEMBL25454479 0.69 ALOX5 (0.43)
SCHEMBL31063009 0.68 PTGS2 (0.46)
SCHEMBL13918218 0.68 ESR1 (0.39)
SCHEMBL14325350 0.68 ALDH1A1 (0.42) RARGRXRAPPARG
SCHEMBL17552740 0.67 RIPK1 (0.40)
SCHEMBL12121971 0.67 PTGS2 (0.52)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665339-A1 INHIBITING ALPHA V BETA 8 INTEGRIN Morphic Therapeutic, Inc. (US) 2025-12-24 EP disclosed
WO-2024173570-A1 INHIBITING αvβ8 INTEGRIN MORPHIC THERAPEUTIC, INC. (US) 2024-08-22 WO disclosed