Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.43 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31063878 | 0.79 | THRB (0.39) | DRD2POLBNPC1ALDH1A1LMNA | |
| SCHEMBL38663599 | 0.77 | GPR119 (0.38) | AOC3DRD2GPR119LMNAPPARA | |
| SCHEMBL20093214 | 0.77 | KEAP1 (0.51) | SYKKMT2A | |
| SCHEMBL20092109 | 0.75 | SYK (0.48) | SYK | |
| SCHEMBL23153752 | 0.74 | AOC3 (0.36) | AOC3DRD2GPR119HTR2APPARA | |
| SCHEMBL30964050 | 0.74 | RAB9A (0.41) | AOC3DRD2HTR2AKDM4ENPC1 | |
| SCHEMBL38664691 | 0.74 | VCAM1 (0.39) | AOC3DRD2GPR119KDM4ENPC1 | |
| SCHEMBL24064173 | 0.74 | ALDH1A1 (0.56) | AOC3KDM4EPOLBALDH1A1CYP3A4 | |
| SCHEMBL20092312 | 0.73 | TYK2 (0.46) | SYKHPGDLMNAL3MBTL1 | |
| SCHEMBL17785817 | 0.72 | PIK3CD (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024165000-A1 | PYRIDAZINE COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海华汇拓医药科技有限公司 | 2024-08-15 | — | — | WO | disclosed |