Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29367884 | 0.83 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL25207020 | 0.83 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL18969539 | 0.81 | KDM4E (0.42) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL1423541 | 0.77 | L3MBTL1 (0.49) | L3MBTL1KDM4EALDH1A1SMN1; SMN2MTNR1A | |
| SCHEMBL30988432 | 0.76 | ROCK1 (0.63) | L3MBTL1ROCK1 | |
| SCHEMBL18938869 | 0.76 | ROCK2 (0.45) | L3MBTL1SMN1; SMN2ROCK1MTNR1AMTNR1B | |
| SCHEMBL27425388 | 0.76 | ROCK1 (0.63) | L3MBTL1ROCK1 | |
| SCHEMBL3056564 | 0.73 | L3MBTL1 (0.59) | L3MBTL1KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL30436497 | 0.73 | L3MBTL1 (0.40) | L3MBTL1KDM4EMAPTLMNA | |
| SCHEMBL26853784 | 0.73 | L3MBTL1 (0.40) | L3MBTL1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240254114-A1 | PREPARATION OF FUSED AZOLE DERIVATIVES AS NOVEL DIACYLGLYCERIDE 0-ACYLTRANSFERASE 2 INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-08-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240254114-A1 | PREPARATION OF FUSED AZOLE DERIVATIVES AS NOVEL DIACYLGLYCERIDE 0-ACYLTRANSFERASE 2 INHIBITORS | DGAT2, DGAT1, ACAT2 | L3MBTL1 2035/4885KDM4E 2128/4885ALDH1A1 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.