Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776048 | 0.85 | GABRA1 (0.50) | ACHECES2CA5AMEN1MAPT | |
| SCHEMBL1204142 | 0.85 | CA5A (0.48) | ACHECA5AMEN1MAPTKMT2A | |
| SCHEMBL17896562 | 0.84 | HCAR1 (0.53) | ACHECES2CES1SLC6A3MAPT | |
| SCHEMBL1198922 | 0.84 | CES2 (0.52) | CES2CES1CA5ARXRARXRB | |
| SCHEMBL9967857 | 0.82 | PARP1 (0.46) | ACHECES2CES1SLC6A3MEN1 | |
| SCHEMBL319123 | 0.80 | CES2 (0.62) | CES2CES1CA5ASLC6A3MAPT | |
| SCHEMBL12187542 | 0.80 | CES2 (0.57) | ACHECES2CA5AMAPTRXRA | |
| SCHEMBL27186673 | 0.78 | RXRA (0.38) | ACHECES2CES1CA5ASLC6A3 | |
| SCHEMBL29799778 | 0.78 | RXRA (0.38) | ACHECES2CES1CA5ASLC6A3 | |
| SCHEMBL16261236 | 0.78 | RXRA (0.50) | ACHECA5AMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4648762-A2 | PPARG MODULATORS | University of Florida Research Foundation, Incorporated (US) | 2025-11-19 | — | — | EP | disclosed |
| WO-2024151519-A2 | PPARG MODULATORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATIN, INCORPORATED (US) | 2024-07-18 | — | — | WO | disclosed |