SCHEMBL319123

SCHEMBL319123

CC(=O)c1cc(F)cc(F)c1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.62
CES1 P23141 3/20 0.62
CA5A P35218 1/20 0.52
HCAR1 Q9BXC0 1/20 0.44
SLC6A3 Q01959 1/20 0.44
LMNA P02545 2/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
HCAR2 Q8TDS4 1/20 0.38
PARP1 P09874 1/20 0.38
GRM5 P41594 1/20 0.38
GAA P10253 1/20 0.38
KIF11 P52732 1/20 0.37
MAOB P27338 1/20 0.37
HPGD P15428 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
KMT2A Q03164 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21643442 0.85 CA5A (0.70) CES2CES1CA5AHCAR1LMNA
SCHEMBL765387 0.85 CES2 (0.46) CES2CES1CA5AHCAR1SLC6A3
SCHEMBL1764905 0.84 CES2 (0.44) CES2CES1CA5AHCAR1SLC6A3
SCHEMBL1160981 0.84 TAS1R3 (0.46) CES2CES1CA5AHCAR1LMNA
SCHEMBL18854453 0.82 CA5A (0.46) CES2CES1CA5AHCAR1LMNA
SCHEMBL1198922 0.80 CES2 (0.52) CES2CES1CA5AGAAKIF11
SCHEMBL5151998 0.80 CES2 (0.41) CES2CES1CA5AHCAR1SLC6A3
SCHEMBL12808620 0.80 CYP4F2 (0.56) CES2CES1CA5AHCAR1LMNA
SCHEMBL765948 0.80 CES2 (0.46) CES2CES1CA5AHCAR1SLC6A3
SCHEMBL1765000 0.80 LMNA (0.47) CES2CES1CA5ALMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 564 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119614529-A Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-03-14 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-116144617-A NADH dependent alcohol dehydrogenase CpSADH, coding gene, strain and application 浙江工业大学 2023-05-23 CN claimed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN claimed
CN-107337620-B 2- amide groups b-sulfonamide compound, preparation method and the purposes as fungicide, herbicide 沈阳农业大学 2019-07-26 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-4735423-A1 KV7 MODULATORS Saniona A/S (DK) 2026-05-06 EP disclosed
EP-4695242-A1 NOVEL SUBSTITUTED PYRROLE COMPOUNDS, COMPOSITIONS COMPRISING THE SUBSTITUTED PYRROLE COMPOUND, AND METHODS OF USE THEREOF Meta Pharmaceuticals (HK) Limited (HK) 2026-02-18 EP disclosed
WO-2025215121-A1 HEDGEHOG ACYLTRANSFERASE INHIBITORS IMPERIAL COLLEGE INNOVATIONS LIMITED (GB) 2025-10-16 WO disclosed
US-20250122171-A1 Substituted Amine Compounds, Compositions and Methods of Use DEEP APPLE THERAPEUTICS, INC. 2025-04-17 US disclosed
WO-2025064534-A1 SUBSTITUTED AMINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2025-03-27 WO disclosed
CN-119614529-A Short-chain dehydrogenase, engineering bacteria and application thereof in asymmetric reduction of potential chiral carbonyl compounds 杭州文德阶生物科技有限公司 2025-03-14 CN disclosed
US-5717116-A TREATING A MIXTURE OF PHENYLHALOGENOMETHYLCARBINOLS WITH A LIPASE IN THE PRESENCE OF A CARBOXYLATE FOLLOWED BY CYCLIZATION WITH A BASE SUMIKA FINE CHEMICALS COMPANY, LIMITED (JP) 1998-02-10 US disclosed
US-5618547-A ADMINISTERING PERFLUOROALKYL GROUP-CONTAINING PHENYL PROPANEDIONE DERIVATIVES BRITISH TECHNOLOGY GROUP LIMITED (GB) 1997-04-08 US disclosed
EP-0735142-A2 Process for producing (R)-styrene oxides SUMIKA FINE CHEMICAL COMPANY, LTD. (JP) 1996-10-02 EP disclosed
EP-0435794-A1 Alkenyl- or heteroaryl thio, sulfone, sulfoxy herbicides RHONE-POULENC AGROCHIMIE (FR) 1991-07-03 EP disclosed
US-4870109-A ANIMAL HUSBANDRY ELI LILLY AND COMPANY (US) 1989-09-26 US disclosed
EP-0317275-A2 Control of ectoparasites BRITISH TECHNOLOGY GROUP USA INC. (US) 1989-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122171-A1 Substituted Amine Compounds, Compositions and Methods of Use MRGPRX2, MRGPRX1, MRGPRX4 CES2 158/4885CES1 843/4885CA5A 924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.