Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | MTOR | P42345 | 5/20 | 0.35 |
| ▸ | GCK | P35557 | 1/20 | 0.34 |
| ▸ | GCKR | Q14397 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073262 | 0.95 | HRH3 (0.36) | HRH3HRH4PIK3CAMTORRPS6KB1 | |
| SCHEMBL31073153 | 0.85 | DHFR (0.34) | PIK3CAMTORGCKGCKR | |
| SCHEMBL31073086 | 0.85 | TRPC6 (0.36) | GCKGCKR | |
| SCHEMBL31072986 | 0.83 | KCNH2 (0.41) | HRH3 | |
| SCHEMBL31073239 | 0.83 | DRD4 (0.40) | GCKGCKR | |
| SCHEMBL31073285 | 0.82 | GCK (0.38) | HRH3HRH4PIK3CAMTORGCK | |
| SCHEMBL31073195 | 0.81 | PIK3CA (0.40) | HRH3HRH4PIK3CAMTORGCK | |
| SCHEMBL31073137 | 0.81 | GCK (0.37) | PIK3CAMTORGCKGCKR | |
| SCHEMBL31073273 | 0.80 | USP14 (0.33) | GCKGCKR | |
| SCHEMBL31073384 | 0.78 | CHKA (0.40) | HRH3HRH4PIK3CAMTORRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |