Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.35 |
| ▸ | MTOR | P42345 | 5/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31073006 | 0.95 | HRH3 (0.38) | HRH3RPS6KB1PIK3CAMTORHRH4 | |
| SCHEMBL31073153 | 0.88 | DHFR (0.34) | PIK3CAMTORAOC3GPR119 | |
| SCHEMBL31072986 | 0.86 | KCNH2 (0.41) | HRH3 | |
| SCHEMBL31073285 | 0.85 | GCK (0.38) | HRH3RPS6KB1PIK3CAMTORHRH4 | |
| SCHEMBL31073195 | 0.84 | PIK3CA (0.40) | HRH3PIK3CAMTORHRH4 | |
| SCHEMBL31073086 | 0.84 | TRPC6 (0.36) | — | |
| SCHEMBL31073373 | 0.83 | POLB (0.48) | HRH3MAPTSMN1; SMN2GPR119 | |
| SCHEMBL31073430 | 0.83 | POLB (0.48) | HRH3MAPTSMN1; SMN2GPR119 | |
| SCHEMBL31073002 | 0.82 | GCK (0.38) | HRH3AOC3GPR119 | |
| SCHEMBL31073142 | 0.82 | CHRNB2 (0.33) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024173646-A1 | CYCLIN-DEPENDENT KINASE DEGRADING COMPOUNDS | INNOVO THERAPEUTICS, INC. (US) | 2024-08-22 | — | — | WO | disclosed |