Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | HTR2B | P41595 | 3/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30996992 | 0.79 | NPC1 (0.49) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL28635892 | 0.75 | HTR2B (0.59) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL27942181 | 0.74 | PNMT (0.49) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL5837265 | 0.74 | PNMT (0.49) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL2043313 | 0.74 | PNMT (0.49) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL7877087 | 0.74 | PNMT (0.49) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL28668245 | 0.72 | NPC1 (0.49) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL524602 | 0.72 | PNMT (0.63) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL30103334 | 0.72 | PNMT (0.63) | PNMTHTR2BHTR7NPC1RAB9A | |
| SCHEMBL8971039 | 0.71 | PNMT (0.46) | PNMTHTR2BHTR7NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246918-A1 | COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND THE USES THEREOF | RIBOMETRIX, INC. | 2024-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246918-A1 | COMPOUNDS AND COMPOSITIONS AS EIF4E INHIBITORS AND THE USES THEREOF | EIF4E, EIF4EBP1, EIF4A1 | PNMT 2801/4885HTR2B 4446/4885HTR7 4477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.