Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16040183 | 0.83 | HTR3A (0.45) | KDM4EALDH1A1HSD17B10XDHDRD2 | |
| SCHEMBL31078751 | 0.73 | HSD17B14 (0.49) | KDM4EALDH1A1LMNATP53 | |
| SCHEMBL2430511 | 0.71 | KDM4E (0.56) | KDM4EALDH1A1L3MBTL1HSD17B10NPC1 | |
| SCHEMBL16040909 | 0.70 | KDM4E (0.43) | KDM4EALDH1A1L3MBTL1HSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL4284877 | 0.70 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1HSD17B10NPC1 | |
| SCHEMBL20854390 | 0.70 | KDM4E (0.49) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2800959 | 0.69 | PRKAB2 (0.39) | KDM4EALDH1A1HSD17B10XDHDRD2 | |
| Hydrochloric Acid SCHEMBL31608762 | 0.68 | USP28 (0.37) | DRD2DRD4DRD3DRD1HTR2A | |
| SCHEMBL16631725 | 0.68 | CTSA (0.40) | KDM4EALDH1A1L3MBTL1HSD17B10SMN1; SMN2 | |
| SCHEMBL14857791 | 0.68 | ALDH1A1 (0.39) | KDM4EALDH1A1L3MBTL1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |