SCHEMBL310857

SCHEMBL310857

C=CC(=O)N(CC(C)=O)CC(C)=O

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
ZDHHC20 Q5W0Z9 2/20 0.38
ZDHHC2 Q9UIJ5 1/20 0.38
TSHR P16473 2/20 0.35
PSMB5 P28074 2/20 0.33
TDP1 Q9NUW8 1/20 0.30
TP53 P04637 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16285077 0.79 MGAM (0.41) ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5
SCHEMBL12831950 0.78 ALDH1A1 (0.39) ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5
SCHEMBL6402606 0.77 LMNA (0.38) ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5
SCHEMBL4365703 0.76 ZDHHC20 (0.40) ALDH1A1ZDHHC20ZDHHC2TSHRLMNA
SCHEMBL16285114 0.76 ZDHHC20 (0.36) ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5
SCHEMBL16281562 0.76 CA12 (0.44) ALDH1A1ZDHHC20ZDHHC2TSHRPSMB5
SCHEMBL224019 0.76
SCHEMBL14880 0.74
Water SCHEMBL11778100 0.74 ZDHHC20 (0.40) ALDH1A1ZDHHC20ZDHHC2TSHRTDP1
SCHEMBL423989 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103565558-B High-strength double-network hydrogel/bioceramic composite stent and preparation method thereof UNIV XI AN JIAOTONG 2015-07-01 CN claimed
CN-103071187-B Ligament-bone composite scaffold with biomimetic connecting interface and forming method thereof UNIV XI AN JIAOTONG 2014-04-23 CN claimed
CN-103565558-A High-strength double-network hydrogel/bioceramic composite stent and preparation method thereof UNIV XI AN JIAOTONG 2014-02-12 CN claimed
CN-102335460-B Magnesium alloy/biological ceramic bone bracket based on photocuring and gel casting and forming method of bone bracket UNIV XI AN JIAOTONG 2014-01-29 CN claimed
EP-2629780-A2 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS 206 ORTHO, Inc. (US) 2013-08-28 EP claimed
US-20120101593-A1 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS BIOS2 Medical, Inc. (US) 2012-04-26 US claimed
WO-2012054742-A2 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS BIOS2 Medical, Inc. (US) 2012-04-26 WO claimed
EP-0932652-B2 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF SE (DE) 2008-04-23 EP claimed
US-6610278-B2 Hardness not greater than 75 as measured by an Asker rubber-hardness tester type C1L; a porosity of at least 0.4; and an impact resistance of at least 5; excellent skin feel upon use and is not easily broken. KAO CORPORATION (JP) 2003-08-26 US claimed
EP-0932652-B1 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF AG (DE) 2002-12-18 EP claimed
US-20020028220-A1 POWDER-BASED SOLID COSMETIC COMPOSITION AND PREPARATION PROCESS THEREOF KAO CORPORATION (JP) 2002-03-07 US claimed
EP-0932652-A1 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1999-08-04 EP claimed
WO-1998016589-A1 USE OF POLYMER DISPERSIONS AS BINDING AGENTS FOR SEALING COMPOUNDS AND COATING COMPOUNDS BASF AKTIENGESELLSCHAFT (DE) 1998-04-23 WO claimed
EP-0188110-B1 Hydrogel-forming polymers TR DEV LTD (GB) 1995-09-06 EP claimed
US-4687689-A CROSSLINKING TOYO SEIKAN KAISHA, LTD. (JP) 1987-08-18 US claimed
JP-63106743-A None JP disclosed
EP-3838934-B1 ADHESIVE COMPOSITION FOR PAPER BONDING TESA SE (DE) 2025-05-14 EP disclosed
US-4067927-A TEXTILES STAUFFER CHEMICAL COMPANY (US) 1978-01-10 US disclosed
US-4052158-A CATALYTIC FREE RADICAL POLYMERIZATION, CURING STAUFFER CHEMICAL COMPANY (US) 1977-10-04 US disclosed
US-4017257-A Textiles fire-retardant treated with copolycondensed vinylphosphonates and process STAUFFER CHEMICAL COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020028220-A1 POWDER-BASED SOLID COSMETIC COMPOSITION AND PREPARATION PROCESS THEREOF CUTA, C1R, C1S ALDH1A1 3005/4885ZDHHC20 853/4885ZDHHC2 2077/4885
US-20120101593-A1 IMPLANTABLE POLYMER FOR BONE AND VASCULAR LESIONS BMP2, SOST, CD47 ALDH1A1 2935/4885ZDHHC20 4505/4885ZDHHC2 4493/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.