Sugi Predict

Sugi Predict / Compounds / SCHEMBL310906

SCHEMBL310906

SCHEMBL310906

O=[N+]([O-])c1cc(F)c(Br)cc1F

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ATM Q13315 1/20 0.55
▸ TDP1 Q9NUW8 1/20 0.55
▸ MAPT P10636 5/20 0.49
▸ PKM P14618 1/20 0.49
▸ ALDH1A1 P00352 4/20 0.48
▸ HIF1A Q16665 1/20 0.48
▸ MAPK1 P28482 2/20 0.47
▸ VCAM1 P19320 1/20 0.46
▸ ESPL1 Q14674 1/20 0.44
▸ CYP3A4 P08684 2/20 0.42
▸ VCP P55072 1/20 0.41
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ CYP1A2 P05177 2/20 0.38
▸ CTSB P07858 1/20 0.38
▸ HSPB1 P04792 1/20 0.38
▸ CYP2D6 P10635 1/20 0.37
▸ CYP2C9 P11712 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ RAB9A P51151 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740055 1.00 ATM (0.55) ATMTDP1MAPTPKMALDH1A1
SCHEMBL7335 0.91 ATM (0.55) ATMTDP1MAPTPKMALDH1A1
SCHEMBL29663529 0.91 ATM (0.55) ATMTDP1MAPTPKMALDH1A1
SCHEMBL18905090 0.89 TDP1 (0.52) ATMTDP1MAPTPKMALDH1A1
SCHEMBL7759334 0.87 MAPT (0.53) ATMTDP1MAPTPKMALDH1A1
SCHEMBL4397890 0.87 MAPT (0.53) ATMTDP1MAPTPKMALDH1A1
SCHEMBL30598678 0.87 MAPT (0.53) ATMTDP1MAPTPKMALDH1A1
SCHEMBL4670199 0.86 TDP1 (0.62) ATMTDP1MAPTPKMALDH1A1
SCHEMBL29495221 0.84 MAPT (0.59) ATMTDP1MAPTPKMALDH1A1
SCHEMBL2536509 0.84 MAPT (0.59) ATMTDP1MAPTPKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 467 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7285896-A — — None — — JP disclosed
US-20260047267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-12 — — US disclosed
EP-3976604-B1 1,3,4-OXADIAZOLE DERIVATIVE COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITOR, AND THE PHARMACEUTICAL COMPOSITION COMPRISING THE SAME CHONG KUN DANG PHARMACEUTICAL CORP (KR) 2026-01-21 — — EP disclosed
US-12528810-B2 Small molecule inhibitors of DYRK/CLK and uses thereof ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2026-01-20 — — US disclosed
US-20260014147-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2026-01-15 — — US disclosed
US-20250346593-A1 IMIDAZO(1,2-1)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS INTERLINE THERAPEUTICS INC (US) 2025-11-13 — — US disclosed
US-12466815-B2 Carboxamide compounds and uses thereof INCYTE CORPORATION (US) 2025-11-11 — — US disclosed
US-20250325677-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-23 — — US disclosed
US-20250320206-A1 STAT6 DEGRADERS GILEAD SCIENCES INC (US) 2025-10-16 — — US disclosed
US-20250302815-A1 PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS CALICO LIFE SCIENCES LLC 2025-10-02 — — US disclosed
US-5622961-A PROSTATE CANCER, SKIN DISORDERS, BALDNESS ELI LILLY AND COMPANY (US) 1997-04-22 — — US disclosed
US-5622962-A PROSTATE CANCER, SKIN DISORDERS, BALDNESS ELI LILLY AND COMPANY (US) 1997-04-22 — — US disclosed
US-5578724-A INHIBITORS OF 5-ALPHA-REDUCTASE ELI LILLY AND COMPANY (US) 1996-11-26 — — US disclosed
WO-1996035422-A1 METHODS FOR INHIBITING BONE LOSS ELI LILLY AND COMPANY (US) 1996-11-14 — — WO disclosed
EP-0742010-A2 Benzoquinolin-3-ones to inhibit bone loss ELI LILLY AND COMPANY (US) 1996-11-13 — — EP disclosed
EP-0733365-A2 Use of benzoquinolin-3-ones for the treatment and prevention of prostatic cancer ELI LILLY AND COMPANY (US) 1996-09-25 — — EP disclosed
EP-0732942-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1996-09-25 — — EP disclosed
US-5550134-A ADMINISTERING TO A MAMMAL FROM A SERIES OF BENZOQUINOLIN-3-ONE COMPOUNDS ELI LILLY AND COMPANY (US) 1996-08-27 — — US disclosed
JP-H07285896-A 1,4-DIFLUOROBENZENE DERIVATIVE IHARA CHEM IND CO LTD 1995-10-31 — — JP disclosed
WO-1995012417-A1 ALKYL, AZIDO, ALKOXY, AND FLUORO-SUBSTITUTED AND FUSED QUINOXALINEDIONES AND THE USE THEREOF AS GLYCINE RECEPTOR ANTAGONISTS ACEA PHARMACEUTICALS, INC. (US) 1995-05-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12528810-B2 Small molecule inhibitors of DYRK/CLK and uses thereof CLK3, CLK2, CLK1 ATM 335/4885TDP1 382/4885MAPT 890/4885
US-20250325677-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 ATM 1026/4885TDP1 1466/4885MAPT 1017/4885
US-20250302815-A1 PROTEIN TYROSINE PHOSPHATASE TARGETING LIGANDS PTPN1, PTPN2, PTPN18 ATM 629/4885TDP1 1313/4885MAPT 2823/4885
US-20250346593-A1 IMIDAZO(1,2-1)PYRIDINE DERIVATIVES AS RIPK2 INHIBITORS RIPK2, RIPK1, RIPK4 ATM 1294/4885TDP1 938/4885MAPT 2531/4885
US-20260014147-A1 STAT6 DEGRADERS STAT6, NCOR1, CBR1 ATM 2235/4885TDP1 1465/4885MAPT 4225/4885
US-12466815-B2 Carboxamide compounds and uses thereof PCK1, PHKG2, PHKG1 ATM 2308/4885TDP1 1427/4885MAPT 4247/4885
US-20260047267-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LBR, OXER1, NPY1R ATM 4017/4885TDP1 3369/4885MAPT 3928/4885
US-20250320206-A1 STAT6 DEGRADERS STAT6, STAT5B, STAT1 ATM 1026/4885TDP1 1466/4885MAPT 1017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.