Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.59 |
| ▸ | RXRB | P28702 | 1/20 | 0.59 |
| ▸ | RXRG | P48443 | 1/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.58 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825765 | 0.94 | CTSV (0.58) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL591616 | 0.88 | FOLH1 (0.55) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL12659905 | 0.88 | MCL1 (0.60) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL4437175 | 0.88 | RXRA (0.52) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL16077693 | 0.87 | RXRA (0.52) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL24983814 | 0.86 | ALDH1A1 (0.54) | RXRARXRBRXRGMCL1FFAR4 | |
| SCHEMBL12941391 | 0.86 | RXRA (0.51) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL12659913 | 0.86 | RXRA (0.58) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL10256205 | 0.86 | MCL1 (0.54) | RXRARXRBRXRGMCL1FOLH1 | |
| SCHEMBL30892473 | 0.85 | FOLH1 (0.65) | MCL1FOLH1PTGER1L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108101870-B | Preparation method of active ingredient for selectively treating glaucoma and related salt thereof | 盐城师范学院 | 2020-03-06 | — | — | CN | disclosed |
| US-20100179218-A1 | OCULOSELECTIVE DRUGS AND PRODRUGS | QLT INC. (CA) | 2010-07-15 | — | — | US | disclosed |
| US-20100179218-A1 | OCULOSELECTIVE DRUGS AND PRODRUGS | QLT INC. (CA) | 2010-07-15 | — | — | US | disclosed |
| US-7678829-B2 | Oculoselective drugs and prodrugs | QLT INC. (CA) | 2010-03-16 | — | — | US | disclosed |
| US-7678829-B2 | Oculoselective drugs and prodrugs | QLT INC. (CA) | 2010-03-16 | — | — | US | disclosed |
| US-20070254950-A1 | Oculoselective Drugs and Prodrugs | OTHERA PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| US-20070254950-A1 | Oculoselective Drugs and Prodrugs | OTHERA PHARMACEUTICALS, INC. (US) | 2007-11-01 | — | — | US | disclosed |
| EP-1750693-A1 | OCULOSELECTIVE DRUGS AND PRODRUGS | Othera Pharmaceuticals, Inc. (US) | 2007-02-14 | — | — | EP | disclosed |
| US-20060019955-A1 | Oculoselective drugs and prodrugs | OTHERA PHARMACEUTICALS, INC. (US) | 2006-01-26 | — | — | US | disclosed |
| WO-2005115375-A1 | OCULOSELECTIVE DRUGS AND PRODRUGS | OTHERA PHARMACEUTICALS, INC. (US) | 2005-12-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019955-A1 | Oculoselective drugs and prodrugs | HCAR3, CNKSR1, HCRTR1 | RXRA 90/4885RXRB 45/4885RXRG 81/4885 |
| US-20100179218-A1 | OCULOSELECTIVE DRUGS AND PRODRUGS | ALDH1A2, CYP2D6, PDE6C | RXRA 431/4885RXRB 235/4885RXRG 236/4885 |
| US-20070254950-A1 | Oculoselective Drugs and Prodrugs | CNKSR1, HCAR3, HCRTR1 | RXRA 73/4885RXRB 31/4885RXRG 66/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.