SCHEMBL311328

SCHEMBL311328

O=[N+]([O-])c1cccc2nc[nH]c12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TXNRD1 Q16881 1/20 0.49
TXNRD3 Q86VQ6 1/20 0.49
TXNRD2 Q9NNW7 1/20 0.49
POLB P06746 1/20 0.49
TDP1 Q9NUW8 3/20 0.47
CYP3A4 P08684 2/20 0.47
APEX1 P27695 2/20 0.47
MAPT P10636 2/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 1/20 0.47
CYP1A2 P05177 1/20 0.47
THRB P10828 1/20 0.47
HPGD P15428 1/20 0.47
TSHR P16473 1/20 0.47
NOS3 P29474 1/20 0.47
NOS1 P29475 1/20 0.47
CYP2C19 P33261 1/20 0.47
NOS2 P35228 1/20 0.47
RECQL P46063 1/20 0.47
BLM P54132 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21359970 0.91 POLB (0.42) TXNRD1TXNRD3TXNRD2POLBTDP1
Phosphoramidic Acid SCHEMBL312859 0.89 POLB (0.41) TXNRD1TXNRD3TXNRD2POLBTDP1
Morpholine SCHEMBL27607357 0.86 POLB (0.41) TXNRD1TXNRD3TXNRD2POLBTDP1
SCHEMBL28326417 0.86 MEN1 (0.39) TXNRD1TXNRD3TXNRD2POLBTDP1
SCHEMBL29395442 0.83 POLB (0.46) TXNRD1TXNRD3TXNRD2POLBTDP1
SCHEMBL28202812 0.78 PARP1 (0.57) TXNRD1TXNRD3TXNRD2POLBTDP1
SCHEMBL5675915 0.78 CLK1 (0.50) POLBTDP1CYP3A4APEX1MAPT
SCHEMBL6142552 0.76 CYP3A4 (0.46) TDP1CYP3A4MAPTMEN1CYP1A2
Nitric Acid SCHEMBL14695341 0.76 CYP3A4 (0.39) TXNRD1TXNRD3TXNRD2POLBTDP1
SCHEMBL4518440 0.75 ALDH1A1 (0.48) TXNRD1TXNRD3TXNRD2POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1059 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630851-B2 Polynucleotide modification methods OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-19 US claimed
US-12624387-B2 Method for reducing primer dimer formation and increasing amplification efficiency SEEGENE, INC. (KR) 2026-05-12 US claimed
US-12584168-B2 Sample preparation method OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-24 US claimed
US-12371736-B2 TD probe and its uses SEEGENE, INC. (KR) 2025-07-29 US claimed
WO-2024136630-A1 METHOD FOR SEQUENCE HOMOLOGY SEARCH OF NUCLEOTIDE DATABASE 주식회사 씨젠 2024-06-27 WO claimed
EP-4293127-A2 METHOD FOR REDUCING PRIMER DIMER FORMATION AND INCREASING AMPLIFICATION EFFICIENCY Seegene, Inc. (KR) 2023-12-20 EP claimed
EP-4001428-B1 METHOD FOR REDUCING PRIMER DIMER FORMATION AND INCREASING AMPLIFICATION EFFICIENCY SEEGENE INC (KR) 2023-11-22 EP claimed
EP-3286338-B1 AMPLIFICATION WITH PRIMERS OF LIMITED NUCLEOTIDE COMPOSITION Atila Biosystems Incorporated (US) 2023-11-01 EP claimed
CN-110168103-B Methods for reducing primer dimer formation and increasing amplification efficiency SEEGENE株式会社 2023-09-08 CN claimed
US-20230250474-A1 SAMPLE PREPARATION METHOD OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2023-08-10 US claimed
US-20050164184-A1 Hybridization portion control oligonucleotide and its uses SEEGENE, INC. (KR) 2005-07-28 US claimed
WO-2005045073-A1 METHOD FOR AMPLIFYING UNKNOWN DNA SEQUENCE ADJACENT TO KNOWN SEQUENCE SEEGENE, INC. (KR) 2005-05-19 WO claimed
CN-1602361-A Hybridization portion control oligonucleotide and use thereof SEEGENE INC (KR) 2005-03-30 CN claimed
CN-1578841-A Annealing control primer and use of the same VISION GENE CO LTD (KR) 2005-02-09 CN claimed
EP-1448795-A1 HYBRIDIZATION PORTION CONTROL OLIGONUCLEOTIDE AND ITS USES Seegene, Inc. (KR) 2004-08-25 EP claimed
EP-1448793-A1 ANNEALING CONTROL PRIMER AND ITS USES Seegene, Inc. (KR) 2004-08-25 EP claimed
US-20030175749-A1 Annealing control primer and its uses SEEGENE, INC. (KR) 2003-09-18 US claimed
US-20030119016-A1 Antisense oligonucleotides with increased RNase sensitivity THIRD WAVE TECHNOLOGIES, INC. 2003-06-26 US claimed
WO-2003050306-A1 HYBRIDIZATION PORTION CONTROL OLIGONUCLEOTIDE AND ITS USES SEEGENE, INC. (KR) 2003-06-19 WO claimed
WO-2003050305-A1 ANNEALING CONTROL PRIMER AND ITS USES SEEGENE, INC. (KR) 2003-06-19 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584168-B2 Sample preparation method POLN, POLRMT, POLM TXNRD1 3056/4885TXNRD3 3966/4885TXNRD2 2319/4885
US-12630851-B2 Polynucleotide modification methods PNP, NT5C3B, UNG TXNRD1 2720/4885TXNRD3 3004/4885TXNRD2 1673/4885
US-20030119016-A1 Antisense oligonucleotides with increased RNase sensitivity RNASE1, RNASEL, RNASEH1 TXNRD1 1030/4885TXNRD3 627/4885TXNRD2 1552/4885
US-12624387-B2 Method for reducing primer dimer formation and increasing amplification efficiency UBR4, UBAP2, UBAP2L TXNRD1 1772/4885TXNRD3 1837/4885TXNRD2 1857/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.