SCHEMBL3113533

SCHEMBL3113533

N#Cc1ccc(OCCF)c(Br)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ S1PR1 P21453 1/20 0.40
▸ FFAR1 O14842 1/20 0.38
▸ F2 P00734 1/20 0.37
▸ PLAU P00749 1/20 0.37
▸ ST14 Q9Y5Y6 1/20 0.37
▸ AR P10275 1/20 0.37
▸ CYP1A2 P05177 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ CYP2C19 P33261 1/20 0.36
▸ MAPT P10636 3/20 0.36
▸ HPGD P15428 3/20 0.36
▸ L3MBTL1 Q9Y468 3/20 0.36
▸ ESRRA P11474 1/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ TTR P02766 1/20 0.36
▸ ALB P02768 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ EPAS1 Q99814 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12187855 0.85 F2 (0.43) FFAR1F2PLAUST14AR
SCHEMBL10760645 0.83 HPGD (0.41) FFAR1F2PLAUST14AR
SCHEMBL10730804 0.83 F2 (0.41) FFAR1F2PLAUST14AR
SCHEMBL6246819 0.82 F2 (0.43) FFAR1F2PLAUST14AR
SCHEMBL2037172 0.82 HPGD (0.43) FFAR1F2PLAUST14AR
SCHEMBL27938601 0.81 HPGD (0.48) S1PR1CYP1A2CYP2D6CYP2C19MAPT
SCHEMBL27920110 0.80 XDH (0.43) FFAR1ARTDP1
SCHEMBL12221683 0.80 L3MBTL1 (0.43) FFAR1ARCYP1A2CYP2D6CYP2C19
SCHEMBL944720 0.79 TRPV4 (0.53) S1PR1FFAR1ARMAPTHPGD
SCHEMBL15024950 0.79 PTGDR2 (0.43) FFAR1F2PLAUST14AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12324845-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2025-06-10 — — US disclosed
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2025-05-22 — — US disclosed
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2022-09-15 — — US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 — — US disclosed
US-11241509-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2022-02-08 — — US disclosed
EP-2474525-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-15 — — EP disclosed
EP-2474523-B1 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING INC (US) 2020-04-08 — — EP disclosed
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2018-11-29 — — US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 — — US disclosed
US-10010631-B2 Ligands for imaging cardiac innervation LANTHEUS MEDICAL IMAGING, INC. (US) 2018-07-03 — — US disclosed
EP-2474524-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474525-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
EP-2474526-A2 Ligands for imaging cardiac innervation Lantheus Medical Imaging, Inc. (US) 2012-07-11 — — EP disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION CITIZENS BANK, N.A. 2010-09-02 — — US disclosed
EP-2114873-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION Lantheus Medical Imaging, Inc. (US) 2009-11-11 — — EP disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 — — WO disclosed
WO-2008083056-A2 LIGANDS FOR IMAGING CARDIAC INNERVATION LANTHEUS MEDICAL IMAGING, INC. (US) 2008-07-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10010631-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 S1PR1 736/4885FFAR1 492/4885F2 4777/4885
US-20100221182-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 S1PR1 736/4885FFAR1 492/4885F2 4777/4885
US-20180339070-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 S1PR1 736/4885FFAR1 492/4885F2 4777/4885
US-20220288243-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 S1PR1 736/4885FFAR1 492/4885F2 4777/4885
US-11241509-B2 Ligands for imaging cardiac innervation TNNT2, PNMT, TNNC1 S1PR1 637/4885FFAR1 419/4885F2 4754/4885
US-20250161500-A1 LIGANDS FOR IMAGING CARDIAC INNERVATION TNNT2, PNMT, TNNC1 S1PR1 736/4885FFAR1 492/4885F2 4777/4885
US-12324845-B2 Ligands for imaging cardiac innervation CHRNB4, RXFP4, RXFP3 S1PR1 604/4885FFAR1 297/4885F2 3049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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