Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL108260 | 0.79 | ALDH1A1 (0.42) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL8746003 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL3266441 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL10476380 | 0.77 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL849826 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL16302318 | 0.76 | ALDH1A1 (0.46) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL3115134 | 0.74 | KDM4E (0.40) | ALDH1A1KMT2AMEN1GAABRD4 | |
| SCHEMBL31472460 | 0.74 | ALDH1A1 (0.45) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL18589183 | 0.74 | MAPK1 (0.42) | ALDH1A1KMT2AMEN1GAAMAPK1 | |
| SCHEMBL6258436 | 0.73 | ALDH1A1 (0.38) | ALDH1A1KMT2AMEN1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1049 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-12-31 | — | — | US | claimed |
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-08 | — | — | US | claimed |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-10-01 | — | — | US | claimed |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | HENKEL AG & CO. KGAA (DE) | 2024-09-24 | — | — | US | claimed |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | HENKEL AG & CO. KGAA (DE) | 2024-03-05 | — | — | US | claimed |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-10-05 | — | — | US | claimed |
| WO-2023163903-A1 | OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | WO | claimed |
| WO-2023163906-A1 | OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | WO | claimed |
| WO-2023163908-A1 | OXIDATIVE DYEING AGENT FOR KERATIN FIBERS COMPRISING NOVEL DYE PRECURSOR COMBINATIONS | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | WO | claimed |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | HENKEL AG & CO. KGAA (DE) | 2023-08-31 | — | — | US | claimed |
| WO-2016020111-A1 | NOVEL OXIDATION DYE INTERMEDIATES OF THE TYPE OF OXY-, THIO-, AND AZA-BIS-BENZENES | HENKEL AG & CO. KGAA (DE) | 2016-02-11 | — | — | WO | claimed |
| US-9132073-B2 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | claimed |
| EP-2816992-A2 | NOVEL OXIDATION DYE PRECURSORS | Henkel AG & Co. KGaA (DE) | 2014-12-31 | — | — | EP | claimed |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-12-11 | — | — | US | claimed |
| US-20140245541-A1 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2014-09-04 | — | — | US | claimed |
| US-8821592-B1 | Oxidation dye precursors | HENKEL AG & CO. KGAA (DE) | 2014-09-02 | — | — | US | claimed |
| EP-2734179-A2 | NOVEL OXIDATION DYE PRECURSORS | Henkel AG & Co. KGaA (DE) | 2014-05-28 | — | — | EP | claimed |
| WO-2013124363-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-08-29 | — | — | WO | claimed |
| WO-2013013861-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-01-31 | — | — | WO | claimed |
| WO-2013013897-A2 | NOVEL OXIDATION DYE PRECURSORS | HENKEL AG & CO. KGAA (DE) | 2013-01-31 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12109291-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | ALDH1A1 40/4885KMT2A 2250/4885MEN1 4617/4885 |
| US-20230270647-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, COX5A | ALDH1A1 28/4885KMT2A 2897/4885MEN1 4819/4885 |
| US-11918671-B2 | Multi-tone hair dyeing method in three steps | TYR, HAO2, HAAO | ALDH1A1 111/4885KMT2A 631/4885MEN1 3135/4885 |
| US-20140245541-A1 | NOVEL OXIDATION DYE PRECURSORS | KRT18, SQOR, NDUFA5 | ALDH1A1 184/4885KMT2A 2058/4885MEN1 4338/4885 |
| US-12102704-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, ALDH2 | ALDH1A1 26/4885KMT2A 1974/4885MEN1 4784/4885 |
| US-20140359951-A1 | NOVEL OXIDATION DYE PRECURSORS | KRT18, COXFA4L2, CYB5R3 | ALDH1A1 106/4885KMT2A 2447/4885MEN1 4591/4885 |
| US-12097274-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | ALDH1A1 28/4885KMT2A 2897/4885MEN1 4819/4885 |
| US-20230310296-A1 | Oxidative Dyeing Agent For Keratin Fibers Comprising Novel Dye Precursor Combinations | KRT18, ALDH5A1, ALDH2 | ALDH1A1 40/4885KMT2A 2250/4885MEN1 4617/4885 |
| US-12178897-B2 | Oxidative dyeing agent for keratin fibers comprising novel dye precursor combinations | KRT18, ALDH5A1, COX5A | ALDH1A1 37/4885KMT2A 2049/4885MEN1 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.