Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31159047 | 0.89 | MMP13 (0.40) | RORCGPR119ALOX5APFEN1HDAC2 | |
| SCHEMBL31158818 | 0.82 | MAPT (0.47) | RORCGPR119HDAC4 | |
| SCHEMBL30726307 | 0.80 | RORC (0.48) | RORC | |
| SCHEMBL31159014 | 0.78 | GPR119 (0.45) | RORCGPR119 | |
| SCHEMBL31158858 | 0.78 | APP (0.42) | RORCGPR119ALOX5APFEN1 | |
| SCHEMBL31159120 | 0.76 | MAPT (0.47) | GPR119 | |
| SCHEMBL31158852 | 0.76 | SMN1; SMN2 (0.40) | RORCGPR119ALOX5APFEN1HDAC2 | |
| SCHEMBL25603154 | 0.75 | NR1H2 (0.39) | GPR119ALOX5APFEN1HDAC2HDAC1 | |
| SCHEMBL31159140 | 0.75 | PDK2 (0.40) | RORCGPR119ALOX5APFEN1 | |
| SCHEMBL31158840 | 0.74 | GPR119 (0.49) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024201248-A1 | COMPOUNDS AND METHODS FOR DEGRADING GSPT1 | PIN THERAPEUTICS, INC. (KR) | 2024-10-03 | — | — | WO | disclosed |