Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510562 | 0.84 | HCAR2 (0.42) | HCAR2 | |
| SCHEMBL13330013 | 0.80 | CYP1A2 (0.38) | CYP1A2CYP3A4KDM4EHPGDCYP2C9 | |
| SCHEMBL3156800 | 0.78 | CYP1A2 (0.54) | LMNAALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL1919419 | 0.75 | CYP1A2 (0.41) | HCAR2LMNAALDH1A1CYP1A2POLB | |
| SCHEMBL31495905 | 0.75 | GPR35 (0.45) | LMNAALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL5513393 | 0.74 | ALDH1A1 (0.63) | LMNAALDH1A1CYP1A2CYP3A4KDM4E | |
| SCHEMBL401252 | 0.74 | HCAR2 (0.38) | HCAR2ALDH1A1CYP1A2CYP3A4GPR35 | |
| SCHEMBL3036660 | 0.74 | CYP1A2 (0.70) | LMNAALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL510531 | 0.74 | KDM4E (0.49) | HCAR2LMNAALDH1A1CYP3A4KDM4E | |
| SCHEMBL30630152 | 0.73 | ALDH1A1 (0.61) | LMNAALDH1A1CYP1A2CYP3A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111699220-B | Squarylium salt compound for display device | 日东电工株式会社 | 2022-08-23 | — | — | CN | disclosed |
| US-11422403-B2 | Squarylium compounds for use in display devices | NITTO DENKO CORPORATION (JP) | 2022-08-23 | — | — | US | disclosed |
| US-20200369889-A1 | SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES | NITTO DENKO CORPORATION (JP) | 2020-11-26 | — | — | US | disclosed |
| EP-3717572-A2 | SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES | Nitto Denko Corporation (JP) | 2020-10-07 | — | — | EP | disclosed |
| CN-111699220-A | Squarylium salt compound for display device | 日东电工株式会社 | 2020-09-22 | — | — | CN | disclosed |
| EP-1853586-B1 | ANTIBACTERIAL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| EP-1853586-B1 | ANTIBACTERIAL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2013-07-24 | — | — | EP | disclosed |
| US-20130150366-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA, INTELLECTUAL PROPERTY (GB) | 2013-06-13 | — | — | US | disclosed |
| US-20130150366-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA, INTELLECTUAL PROPERTY (GB) | 2013-06-13 | — | — | US | disclosed |
| US-20130150366-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA, INTELLECTUAL PROPERTY (GB) | 2013-06-13 | — | — | US | disclosed |
| US-7709503-B2 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2010-05-04 | — | — | US | disclosed |
| EP-2158199-A1 | PIPERIDINE COMPOUNDS AND USES THEREOF | AstraZeneca AB (SE) | 2010-03-03 | — | — | EP | disclosed |
| WO-2008152418-A1 | PIPERIDINE COMPOUNDS AND USES THEREOF | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | WO | disclosed |
| US-20080312255-A1 | PIPERDINE COMPOUNDS AND USES THEREOF-911 | ASTRAZENECA AB (SE) | 2008-12-18 | — | — | US | disclosed |
| CN-101163693-A | Antibacterial piperidine derivatives | ASTRAZENECA AB (SE) | 2008-04-16 | — | — | CN | disclosed |
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| CN-1882568-A | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-12-20 | — | — | CN | disclosed |
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-10-05 | — | — | US | disclosed |
| EP-1664025-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026149-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | PEF1, PEPD, PELP1 | HCAR2 4666/4885LMNA 4252/4885ALDH1A1 976/4885 |
| US-20130150366-A1 | CHEMICAL COMPOUNDS | MRPL21, NISCH, CFTR | HCAR2 2991/4885LMNA 3535/4885ALDH1A1 419/4885 |
| US-11422403-B2 | Squarylium compounds for use in display devices | SQLE, SPR, SYMPK | HCAR2 2817/4885LMNA 3411/4885ALDH1A1 972/4885 |
| US-20080312255-A1 | PIPERDINE COMPOUNDS AND USES THEREOF-911 | NISCH, PIR, QDPR | HCAR2 1403/4885LMNA 2265/4885ALDH1A1 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.