Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3117191 | 0.84 | HCAR2 (0.41) | HCAR2 | |
| SCHEMBL5322610 | 0.84 | ALDH1A1 (0.57) | — | |
| SCHEMBL24709647 | 0.81 | CYP1A2 (0.50) | DAO | |
| SCHEMBL3114362 | 0.81 | DAO (0.36) | HCAR2DAO | |
| SCHEMBL401252 | 0.80 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL3111450 | 0.79 | TOP2A (0.43) | DAO | |
| SCHEMBL1919419 | 0.77 | CYP1A2 (0.41) | HCAR2 | |
| SCHEMBL510531 | 0.76 | KDM4E (0.49) | HCAR2 | |
| SCHEMBL3399851 | 0.76 | KDM4E (0.44) | HCAR2 | |
| SCHEMBL11828305 | 0.75 | JAK2 (0.32) | HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258342-B2 | Class of DNA gyrase and/or topoisomerase IV inhibitors with activity against gram-positive and gram-negative bacteria | UNIVERZA V LJUBLJANI (SI) | 2025-03-25 | — | — | US | disclosed |
| US-20250002455-A1 | NEW N-PHENYLPYRROLAMIDE INHIBITORS OF DNA GYRASE AND TOPOISOMERASE IV WITH ANTIBACTERIAL ACTIVITY | UNIV LJUBLJANI (SI) | 2025-01-02 | — | — | US | disclosed |
| CN-118993926-A | Preparation method of chiral amino acid | 香港大学 | 2024-11-22 | — | — | CN | disclosed |
| US-20240383842-A1 | METHODS OF PREPARING CHIRAL AMINO ACIDS | Laboratory for Synthetic Chemistry and Chemical Biology Limited (CN) | 2024-11-21 | — | — | US | disclosed |
| US-20240351999-A1 | PYRROLYLACYLPIPERIDYLAMINE COMPOUND AND USE THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2024-10-24 | — | — | US | disclosed |
| EP-4353716-A1 | PYRROLE ACYL PIPERYLHYDRAZINE COMPOUND AND USE THEREOF | Institute of Materia Medica, Chinese Academy of Medical Sciences (CN) | 2024-04-17 | — | — | EP | disclosed |
| CN-117843552-A | Resolution method of cis-4-amino-3-methoxypiperidine-1-formate optical isomer | 中国医学科学院药物研究所 | 2024-04-09 | — | — | CN | disclosed |
| CN-115466246-B | Pyrrole amide piperidine amine compound and application thereof | 中国医学科学院药物研究所 | 2024-02-06 | — | — | CN | disclosed |
| EP-4263503-A1 | NEW N-PHENYLPYRROLAMIDE INHIBITORS OF DNA GYRASE AND TOPOISOMERASE IV WITH ANTIBACTERIAL ACTIVITY | Univerza V Ljubljani (SI) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022258038-A1 | PYRROLE ACYL PIPERYLHYDRAZINE COMPOUND AND USE THEREOF | 中国医学科学院药物研究所 | 2022-12-15 | — | — | WO | disclosed |
| EP-1856044-A2 | PYRROLE DERIVATIVES AS DNA GYRASE AND TOPOISOMERASE INHIBITORS | AstraZeneca AB (SE) | 2007-11-21 | — | — | EP | disclosed |
| EP-1853586-A1 | ANTIBACTERIAL PIPERIDINE DERIVATIVES | AstraZeneca AB (SE) | 2007-11-14 | — | — | EP | disclosed |
| EP-1664025-B1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2007-09-19 | — | — | EP | disclosed |
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | ASTRAZENECA AB (SE) | 2006-10-05 | — | — | US | disclosed |
| WO-2006092599-A2 | PYRROLE DERIVATIVES AS DNA GYRASE AND TOPOISOMERASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006092608-A1 | TRICYCLIC DERIVATIVES OF AZETIDINE AND PYRROLE WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-09-08 | — | — | WO | disclosed |
| WO-2006087543-A1 | ANTIBACTERIAL PIPERIDINE DERIVATIVES | ASTRAZENECA AB (SE) | 2006-08-24 | — | — | WO | disclosed |
| WO-2006087548-A2 | PYRROLE DERIVATIVES AS DNA GYRASE AND TOPOISOMERASE INHIBITORS | ASTRAZENECA AB (SE) | 2006-08-24 | — | — | WO | disclosed |
| EP-1664025-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026149-A1 | PYRROL DERIVATIVES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223801-A1 | Pyrrol derivatives with antibacterial activity | PEF1, PEPD, PELP1 | HCAR2 4666/4885DAO 1965/4885 |
| US-20250002455-A1 | NEW N-PHENYLPYRROLAMIDE INHIBITORS OF DNA GYRASE AND TOPOISOMERASE IV WITH ANTIBACTERIAL ACTIVITY | TOP1, TOP2A, TOP2B | HCAR2 4095/4885DAO 2149/4885 |
| US-20240383842-A1 | METHODS OF PREPARING CHIRAL AMINO ACIDS | BCAT1, BCAT2, ME1 | HCAR2 2260/4885DAO 7/4885 |
| US-20240351999-A1 | PYRROLYLACYLPIPERIDYLAMINE COMPOUND AND USE THEREOF | AADAT, PKD1, PCTP | HCAR2 3566/4885DAO 404/4885 |
| US-12258342-B2 | Class of DNA gyrase and/or topoisomerase IV inhibitors with activity against gram-positive and gram-negative bacteria | TOP1, TOP2A, TOP2B | HCAR2 4693/4885DAO 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.