Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184529 | 0.88 | MAPK1 (0.49) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31184452 | 0.87 | MAPK1 (0.51) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31184632 | 0.85 | MAPK1 (0.46) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31184422 | 0.80 | MAPK1 (0.40) | MAPK1HTR2AHTR2CHTR2BIDH1 | |
| SCHEMBL31185026 | 0.79 | KMT2A (0.48) | MAPK1MEN1KMT2A | |
| SCHEMBL31184979 | 0.79 | ALDH1A1 (0.46) | MAPK1MEN1KMT2A | |
| SCHEMBL31184763 | 0.79 | EPHX2 (0.49) | MEN1KMT2ACRBNGRM1 | |
| SCHEMBL31184994 | 0.79 | GRM1 (0.44) | MEN1KMT2ACRBNGRM1 | |
| SCHEMBL31185049 | 0.77 | ALDH1A1 (0.44) | MAPK1KMT2ACRBNGRM1 | |
| SCHEMBL31184891 | 0.77 | KMT2A (0.52) | MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |