Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184698 | 0.87 | CHRM4 (0.36) | JAK2CDK5CDK5R1CHRM4CHRM1 | |
| SCHEMBL31184736 | 0.83 | CDK5 (0.36) | CDK5CDK5R1CHRM4CHRM1CALCRL | |
| SCHEMBL31184692 | 0.81 | JAK2 (0.39) | JAK2KMT2AMEN1TNKS | |
| SCHEMBL31184529 | 0.80 | MAPK1 (0.49) | MAPTKMT2AMEN1 | |
| SCHEMBL31184557 | 0.78 | JAK2 (0.36) | JAK2CHRM4CHRM1CALCRLKMT2A | |
| SCHEMBL31184910 | 0.78 | TRPV1 (0.40) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL31184955 | 0.77 | AHR (0.39) | JAK2MAPTKMT2AMEN1 | |
| SCHEMBL31184406 | 0.77 | POLB (0.43) | MAPT | |
| SCHEMBL31184511 | 0.76 | BRD4 (0.41) | CDK5CDK5R1CHRM4CHRM1CALCRL | |
| SCHEMBL31184574 | 0.74 | ACE (0.37) | CDK5CDK5R1CHRM4CHRM1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |