Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185021 | 0.92 | MAPT (0.36) | ALDH1A1MAPTRECQLMALT1KMT2A | |
| SCHEMBL31184643 | 0.91 | PARP1 (0.37) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL31184638 | 0.91 | PARP1 (0.37) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL31184982 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTTP53POLB | |
| SCHEMBL31184793 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTRECQLMALT1KMT2A | |
| SCHEMBL31185080 | 0.86 | MALT1 (0.53) | ALDH1A1MALT1HPGDSMN1; SMN2 | |
| SCHEMBL31184672 | 0.80 | MAPT (0.36) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL31184478 | 0.80 | MAPT (0.38) | ALDH1A1MAPTRECQLKMT2AMEN1 | |
| SCHEMBL31185102 | 0.78 | POLB (0.44) | ALDH1A1MAPTMALT1HPGDLMNA | |
| SCHEMBL31184736 | 0.78 | CDK5 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |