Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31185021 | 0.91 | MAPT (0.36) | ALDH1A1MAPTPOLBTP53THRB | |
| SCHEMBL31184643 | 0.89 | PARP1 (0.37) | MAPTPOLBCRHBPCRHR2PARP1 | |
| SCHEMBL31184638 | 0.89 | PARP1 (0.37) | MAPTPOLBCRHBPCRHR2PARP1 | |
| SCHEMBL31184579 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPTPOLBTP53 | |
| SCHEMBL31184867 | 0.89 | ALDH1A1 (0.44) | ALDH1A1IMPDH2MAPTCRHBPCRHR2 | |
| SCHEMBL31184789 | 0.87 | ALDH1A1 (0.44) | ALDH1A1IMPDH2MAPTPOLBCYP1A2 | |
| SCHEMBL31184478 | 0.79 | MAPT (0.38) | ALDH1A1MAPTPOLBTP53CRHBP | |
| SCHEMBL31184672 | 0.79 | MAPT (0.36) | ALDH1A1MAPTCRHBPCRHR2PARP1 | |
| SCHEMBL31184778 | 0.78 | MAPT (0.40) | MAPTPOLBGRM1PARP1MET | |
| SCHEMBL31184736 | 0.76 | CDK5 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |