Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CALCRL | Q16602 | 10/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | RAMP1 | O60894 | 3/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184511 | 0.85 | BRD4 (0.41) | CDK5CDK5R1CALCRLCHRM4CHRM1 | |
| SCHEMBL31184907 | 0.83 | JAK2 (0.40) | CDK5CDK5R1CALCRLCHRM4CHRM1 | |
| SCHEMBL31184643 | 0.80 | PARP1 (0.37) | — | |
| SCHEMBL31185021 | 0.80 | MAPT (0.36) | — | |
| SCHEMBL31184638 | 0.80 | PARP1 (0.37) | — | |
| SCHEMBL31184579 | 0.78 | ALDH1A1 (0.42) | — | |
| SCHEMBL31184698 | 0.78 | CHRM4 (0.36) | CDK5CDK5R1CALCRLRAMP1CHRM4 | |
| SCHEMBL31184987 | 0.77 | HTR2B (0.36) | HTR2AHTR2CHTR2BHRH1 | |
| SCHEMBL31184982 | 0.76 | ALDH1A1 (0.42) | — | |
| SCHEMBL31184910 | 0.71 | TRPV1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |