Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.32 |
| ▸ | CFB | P00751 | 3/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184984 | 0.90 | HTR2A (0.38) | HTR2BHTR2AHTR2CTP53THRB | |
| SCHEMBL31185067 | 0.88 | POLB (0.36) | HTR2BHTR2AHTR2CMAPTBRD4 | |
| SCHEMBL31184478 | 0.85 | MAPT (0.38) | TP53MAPTCRHBPCRHR2 | |
| SCHEMBL31184672 | 0.85 | MAPT (0.36) | MAPTCRHBPCRHR2 | |
| SCHEMBL31184793 | 0.83 | ALDH1A1 (0.42) | TP53MAPT | |
| SCHEMBL31184867 | 0.82 | ALDH1A1 (0.44) | MAPTCRHBPCRHR2 | |
| SCHEMBL31184736 | 0.77 | CDK5 (0.36) | HTR2BHTR2AHTR2CHRH1 | |
| SCHEMBL31184359 | 0.77 | POLB (0.47) | TP53MAPT | |
| SCHEMBL31185060 | 0.77 | SMN1; SMN2 (0.47) | TP53MAPT | |
| SCHEMBL31184668 | 0.77 | LMNA (0.42) | HTR2BHTR2AHTR2CMAPTHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |