Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184672 | 0.91 | MAPT (0.36) | ALDH1A1MAPTCRHBPCRHR2CNR1 | |
| SCHEMBL31184478 | 0.91 | MAPT (0.38) | ALDH1A1MAPTCRHBPCRHR2CNR1 | |
| SCHEMBL31184982 | 0.89 | ALDH1A1 (0.42) | ALDH1A1IMPDH2MAPTCRHBPCRHR2 | |
| SCHEMBL31184793 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL31184508 | 0.86 | ALDH1A1 (0.45) | ALDH1A1MAPTCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL31184987 | 0.82 | HTR2B (0.36) | MAPTCRHBPCRHR2 | |
| SCHEMBL31184984 | 0.79 | HTR2A (0.38) | MAPTCRHBPCRHR2MEN1KMT2A | |
| SCHEMBL31185021 | 0.79 | MAPT (0.36) | ALDH1A1MAPTCRHBPCRHR2CNR1 | |
| SCHEMBL31184638 | 0.79 | PARP1 (0.37) | MAPTCRHBPCRHR2CNR1CNR2 | |
| SCHEMBL31184643 | 0.79 | PARP1 (0.37) | MAPTCRHBPCRHR2CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |