Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184955 | 0.86 | AHR (0.39) | AHRNUDT1KMT2AABL1MAPT | |
| SCHEMBL31184422 | 0.84 | MAPK1 (0.40) | CDK4NUDT1MAPK1TSHRKMT2A | |
| SCHEMBL31184845 | 0.83 | SMN1; SMN2 (0.60) | CDK4MAPTTP53SMN1; SMN2NPC1 | |
| SCHEMBL31184544 | 0.82 | HTR2C (0.36) | AHRTSHRKMT2AMAPTTP53 | |
| SCHEMBL31184686 | 0.79 | RXFP2 (0.45) | NUDT1TSHRKMT2AABL1MAPT | |
| SCHEMBL31184979 | 0.79 | ALDH1A1 (0.46) | MAPK1TSHRKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL31184994 | 0.78 | GRM1 (0.44) | TSHRKMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL31184763 | 0.78 | EPHX2 (0.49) | TSHRKMT2AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL31185026 | 0.77 | KMT2A (0.48) | MAPK1TSHRKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8122988 | 0.77 | SMN1; SMN2 (0.55) | AHRKMT2APARP14MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |