Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184828 | 0.82 | CDK4 (0.41) | HTR2CMAPTAHRSLC2A1TSHR | |
| SCHEMBL31184822 | 0.81 | CYP1A2 (0.42) | KMT2ATP53LMNA | |
| SCHEMBL31184992 | 0.81 | MGLL (0.41) | TSHRKMT2ALMNAPOLBKDM4E | |
| SCHEMBL31184615 | 0.80 | LMNA (0.31) | LMNAPOLB | |
| SCHEMBL31184614 | 0.80 | ALDH1A1 (0.40) | MAPTTSHRKMT2ATP53LMNA | |
| SCHEMBL31184568 | 0.79 | MAPK1 (0.32) | TSHRPOLB | |
| SCHEMBL31184642 | 0.79 | ALDH1A1 (0.40) | MAPTTP53POLBKDM4E | |
| SCHEMBL31184767 | 0.79 | MALT1 (0.45) | MAPT | |
| SCHEMBL31184750 | 0.79 | BTK (0.34) | — | |
| SCHEMBL31185053 | 0.78 | TP53 (0.40) | MAPTKMT2ATP53LMNABRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |