Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184828 | 0.86 | CDK4 (0.41) | AHRMAPTTP53SMN1; SMN2NUDT1 | |
| SCHEMBL31184771 | 0.79 | RXFP2 (0.44) | ABL1POLBKDM4EMEN1KMT2A | |
| SCHEMBL31184895 | 0.78 | MGLL (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL31184910 | 0.77 | TRPV1 (0.40) | MAPTSMN1; SMN2LMNAALDH1A1NPSR1 | |
| SCHEMBL31184907 | 0.77 | JAK2 (0.40) | MAPTJAK2MEN1KMT2A | |
| SCHEMBL31185102 | 0.76 | POLB (0.44) | MAPTSMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL31184406 | 0.76 | POLB (0.43) | MAPTSMN1; SMN2LMNAALDH1A1CYP1A2 | |
| SCHEMBL8122988 | 0.76 | SMN1; SMN2 (0.55) | AHRMAPTSMN1; SMN2LMNAJAK2 | |
| SCHEMBL31185080 | 0.76 | MALT1 (0.53) | SMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL31184698 | 0.76 | CHRM4 (0.36) | MAPTSMN1; SMN2ALDH1A1JAK2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |