Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31184987 | 0.88 | HTR2B (0.36) | MAPTHTR2AHTR2CHTR2BBRD4 | |
| SCHEMBL31184984 | 0.87 | HTR2A (0.38) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL31184511 | 0.81 | BRD4 (0.41) | POLBMAPTGAAKMT2ASMN1; SMN2 | |
| SCHEMBL31184672 | 0.80 | MAPT (0.36) | MAPTKMT2AMAPK1SMN1; SMN2LMNA | |
| SCHEMBL31184478 | 0.80 | MAPT (0.38) | POLBMAPTKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL31184793 | 0.78 | ALDH1A1 (0.42) | POLBMAPTKMT2ASMN1; SMN2LMNA | |
| SCHEMBL31184867 | 0.77 | ALDH1A1 (0.44) | MAPTKMT2AMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL31184668 | 0.74 | LMNA (0.42) | PDE4APDE4BPDE4CPDE4DMAPT | |
| SCHEMBL31185060 | 0.72 | SMN1; SMN2 (0.47) | POLBMAPTMAPK1USP2HTT | |
| SCHEMBL31184359 | 0.72 | POLB (0.47) | POLBMAPTMAPK1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024220626-A1 | SMALL MOLECULE MODULATORS OF OGG1 | AZKARRA THERAPEUTICS, INC. (US) | 2024-10-24 | — | — | WO | disclosed |