Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ABL2 | P42684 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3119067 | 1.00 | FBP1 (0.58) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18543104 | 1.00 | FBP1 (0.58) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19439378 | 0.80 | FBP1 (0.59) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19439379 | 0.80 | FBP1 (0.59) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL18543740 | 0.80 | FBP1 (0.59) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL441522 | 0.79 | FBP1 (0.46) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8677538 | 0.79 | TRPA1 (0.49) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL453401 | 0.79 | FBP1 (0.46) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8677541 | 0.79 | TRPA1 (0.49) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28488528 | 0.79 | FBP1 (0.58) | FBP1CYP1A2CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3337785-B1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2020-03-18 | — | — | EP | disclosed |
| US-10377707-B2 | Process for the preparation of lactams from glyoxalic acid | CONOPCO INC. (US) | 2019-08-13 | — | — | US | disclosed |
| US-20180237388-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYCOXYLIC ACID | Conopco, Inc., a/b/a UNILEVER (US) | 2018-08-23 | — | — | US | disclosed |
| EP-3337785-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | Unilever PLC (GB) | 2018-06-27 | — | — | EP | disclosed |
| WO-2017029104-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYOXYLIC ACID | UNILEVER PLC (GB) | 2017-02-23 | — | — | WO | disclosed |
| US-20100179221-A1 | FLUORINE-SUBSTITUTED AMPHETAMINES AND AMPHETAMINE DERIVATIVES AND USE THEREOF | UNIVERSITAT TUBINGEN (DE) | 2010-07-15 | — | — | US | disclosed |
| EP-2121571-A1 | FLUORINE-SUBSTITUTED AMPHETAMINES AND AMPHETAMINE DERIVATIVES AND USE THEREOF | Universität Tübingen (DE) | 2009-11-25 | — | — | EP | disclosed |
| WO-2008113565-A1 | FLUORINE-SUBSTITUTED AMPHETAMINES AND AMPHETAMINE DERIVATIVES AND USE THEREOF | Universität Tübingen (DE) | 2008-09-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100179221-A1 | FLUORINE-SUBSTITUTED AMPHETAMINES AND AMPHETAMINE DERIVATIVES AND USE THEREOF | DBH, SLC6A3, COMT | FBP1 1584/4885CYP1A2 109/4885CYP3A4 280/4885 |
| US-10377707-B2 | Process for the preparation of lactams from glyoxalic acid | GLO1, PGLS, GRHPR | FBP1 58/4885CYP1A2 1664/4885CYP3A4 1039/4885 |
| US-20180237388-A1 | PROCESS FOR THE PREPARATION OF LACTAMS FROM GLYCOXYLIC ACID | PGLS, MGAM, GLA | FBP1 243/4885CYP1A2 1452/4885CYP3A4 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.